The Effects of Systemic Isotretinoin Treatment on Adrenal Steroid and Sex Hormones Level in Severe Acne Vulgaris

UnknownOBSERVATIONAL
Enrollment

40

Participants

Timeline

Start Date

September 15, 2022

Primary Completion Date

June 30, 2023

Study Completion Date

June 30, 2023

Conditions
Acne Vulgaris
Interventions
DIAGNOSTIC_TEST

Hormone

At baseline 17-OH Progesterone, DHEA, DHEAS, Androstenedione, Aldosterone, Testosterone, Dihydrotestosterone, Estradiol, 17-OH Pregnenolone, Androsterone, Cortisol, Corticosterone, 11-Degesterone, 21, -Deoxycortisol, Pregnenolone, 11-Deoxycorticostreone hormones will be evaluated.In addition, the FSH, LH, Prolactin, Estrogen, Testosterone, free testosterone, DHEA-s, SHBG, TSH, T4 hormone levels of the patients will be evaluated from all patients

DRUG

Isotretinoin

İn the 3rd month of isotretinoin treatment, 17-OH Progesterone, DHEA, DHEAS, Androstenedione, Aldosterone, Testosterone, Dihydrotestosterone, Estradiol, 17-OH Pregnenolone, Androsterone, Cortisol, Corticosterone, 11-Degesterone, 21, -Deoxycortisol, Pregnenolone, 11-Deoxycorticostreone hormones will be evaluated.In addition, the FSH, LH, Prolactin, Estrogen, Testosterone, free testosterone, DHEA-s, SHBG, TSH, T4 hormone levels of the patients will be evaluated by ELISA method

Trial Locations (1)

Unknown

RECRUITING

Marmara University School of Medicine,Department of Dermatology., Istanbul

Sponsors

Lead Sponsor

All Listed Sponsors
lead

Marmara University

OTHER

NCT05903716 - The Effects of Systemic Isotretinoin Treatment on Adrenal Steroid and Sex Hormones Level in Severe Acne Vulgaris | Biotech Hunter | Biotech Hunter