NCT05902819View on ClinicalTrials.gov

Reconsolidation Blockade of Intrusive Trauma- and Cocaine-related Memories

NARecruitingINTERVENTIONAL
Enrollment

210

Participants

Timeline

Start Date

May 10, 2023

Primary Completion Date

November 30, 2025

Study Completion Date

January 31, 2026

Conditions
Post-traumatic Stress DisorderCocaine Use Disorder
Interventions
BEHAVIORAL

Imagery

Guided imagery of personal trauma- or cocaine-related memory approximately 120min after study medication was given.

DRUG

Minocycline

Single dose of minocycline (200mg) at each of two imagery sessions; Minocycline is given orally in form of a capsule.

DRUG

Placebo

Single dose of mannitol (100%) at each of two imagery sessions; Placebo is given orally in form of a capsule.

Trial Locations (1)

8032

RECRUITING

Psychiatric University Hospital Zurich, University of Zurich, Zurich

All Listed Sponsors
collaborator

University of Zurich

OTHER

lead

Psychiatric University Hospital, Zurich

OTHER