NCT05899725View on ClinicalTrials.gov

The Efficacy and Safety of Corticosteroids in Combination With Ruxolitinib in the Management of Checkpoint Inhibitor Pneumonia

NARecruitingINTERVENTIONAL
Enrollment

60

Participants

Timeline

Start Date

April 14, 2023

Primary Completion Date

March 1, 2025

Study Completion Date

June 30, 2025

Conditions
Severe Checkpoint Inhibitor Pneumonitis
Interventions
DRUG

Corticosteroids

Initial dosage of corticosteroids is no less than predinisone 1mg/kg/d or other corticosteroids with equal equivalence

DRUG

Corticosteroids and Ruxolitinib

Initial dosage of corticosteroids is no less than predinisone 1mg/kg/d or other corticosteroids with equal equivalence, add-on oral Ruxolitinib 5mg twice a day for 2 weeks, following with Ruxolitinib

Trial Locations (1)

100730

RECRUITING

Department of Respiratory Medicine, Peking Union Medical College Hospita, Beijing

All Listed Sponsors
lead

Peking Union Medical College Hospital

OTHER