Conventional Versus Left Bundle Branch Pacing in TAVI

NANot yet recruitingINTERVENTIONAL
Enrollment

50

Participants

Timeline

Start Date

June 15, 2023

Primary Completion Date

June 15, 2025

Study Completion Date

June 15, 2026

Conditions
Aortic Valve StenosisHeart FailurePacemaker-Induced CardiomyopathyTranscatheter Aortic Valve Implantation
Interventions
DEVICE

Left bundle branch pacemaker

Left bundle branch pacing (LBBP) will be the pacing technique. In brief, after localizing the His bundle area the LBBP lead will be positioned approximately 1-1.5 cm distal to the His bundle position in the right ventricular septum. Before screwing the lead deep into the interventricular septum, the suitable position will be confirmed by fluoroscopic signs and adequate paced QSR morphology. Final lead position will be confirmed according to ECG parameters. Given that the pacing parameters with LBBP are typically low and stable, backup RV lead will not be mandatory.

DEVICE

Conventional pacing

Right ventricular pacing in patients with LVEF ≥ 40% and cardiac resynchronization therapy in patients with LVEF \< 40 %

Trial Locations (1)

1000

University Medical Centre Ljubljana, Ljubljana

All Listed Sponsors
lead

University Medical Centre Ljubljana

OTHER

NCT05895097 - Conventional Versus Left Bundle Branch Pacing in TAVI | Biotech Hunter | Biotech Hunter