The Voice as a Tool to Detect Recurrence of Laryngeal and Hypopharyngeal Cancer

RecruitingOBSERVATIONAL
Enrollment

100

Participants

Timeline

Start Date

August 2, 2023

Primary Completion Date

June 30, 2026

Study Completion Date

June 30, 2026

Conditions
Laryngeal CancerHypopharyngeal Cancer
Interventions
OTHER

Voice recording, ENT (Ear, Nose and Throat) examination including transnasal fiberendoscopy, and VHI-30-questionnaire

"The following speech samples will be recorded from the study participants:~* Standardized, phonetically balanced text~* Sustained, modulated production of five vowels~* Picture description~* Diadochokinetic exercise.~Before starting speech recording, the participant fills in a questionnaire consisting of:~* Health barometer~* Self-rating in terms of stress/fatigue/emotional status.~An Ear, Nose and Throat examination incl. transnasal fiberendoscopy is performed at each visit. The investigators will assess the vocal folds/aryepiglottic folds for the presence of paralysis or reduced mobility, as well as the presence of scar/synechia, edema, erythro-/leukoplakia, or a cancer-suspicious lesion/mass in the larynx/hypopharynx or a chondroradionecrosis in the larynx.~Additionally, it will be assessed, if a tracheotomy canula or a nasogastric tube is in place or was used since the last visit.~Furthermore, the investigators will ask the patients to fill out the VHI-30."

Trial Locations (2)

3010

RECRUITING

Department of Oto-Rhino-Laryngology, Head and Neck Surgery, Inselspital, Bern University Hospital, Bern

8091

RECRUITING

Department of Oto-Rhino-Larnygology, Head and Neck Surgery, University Hospital Zurich, Zurich

All Listed Sponsors
lead

Insel Gruppe AG, University Hospital Bern

OTHER