Zinc Supplementation Prior to Botox Injections for Spasmodic Dysphonia

PHASE1/PHASE2Active, not recruitingINTERVENTIONAL
Enrollment

36

Participants

Timeline

Start Date

August 1, 2023

Primary Completion Date

December 31, 2025

Study Completion Date

December 31, 2025

Conditions
Spasmodic Dysphonia
Interventions
DRUG

Zinc gluconate supplement

Subjects will take a 50 mg zinc gluconate supplement at breakfast for the five days leading up to their next injection appointment. They will also answer questionnaires and provide audio recordings at various time points of the two injection cycles, which is roughly six months.

DRUG

Botulinum toxin type A

This is the current standard of care for treatment of spasmodic dysphonia. Botox injection goes into the vocal cord muscle, and will be occur in both the control and experimental arms of the study.

Trial Locations (1)

32610

University of Florida- Shands Hospital, Gainesville

All Listed Sponsors
lead

University of Florida

OTHER