Effect of Immunonutrients on Oral Mucositis in Nasopharyngeal Carcinoma Patients After Chemoradiotherapy

NARecruitingINTERVENTIONAL
Enrollment

190

Participants

Timeline

Start Date

June 12, 2023

Primary Completion Date

April 30, 2025

Study Completion Date

April 1, 2027

Conditions
Locally Advanced Nasopharyngeal Carcinoma
Interventions
DIETARY_SUPPLEMENT

Enteral immunonutrition

Enteral immunonutrition (Oral Impact®, Nestle), 250ml/ bottle, 2 bottles per day, from 5 days before radiotherapy to the end of radiotherapy.

DIETARY_SUPPLEMENT

Standard enteral nutrition

Isocaloric standard enteral nutrition formula (ENSURE®), 250 mL per administration, 3 times per day. Preparation of the 250 mL dose involves adding 200 mL of potable water to a cup and slowly stirring in 52.7 g of ENSURE powder (approximately 6 scoops).

Trial Locations (20)

266044

RECRUITING

Qingdao Central Hospital, Qingdao

310012

RECRUITING

Zhejiang Provincial Tongde Hospital, Hangzhou

310014

RECRUITING

Zhejiang Provincial People's Hospital, Hangzhou

310022

RECRUITING

Zhejiang Cancer Hospital, Hangzhou

330000

RECRUITING

Second Affiliated Hospital of Nanchang University, Nanchang

330209

RECRUITING

The First Affiliated Hospital of Nanchang University, Nanchang

350000

RECRUITING

Fujian Provincial Hospital, Fuzhou

350014

RECRUITING

Fujian Cancer Hospital, Fuzhou

510060

RECRUITING

Guangdong Provincial People's Hospital, Guangzhou

510070

RECRUITING

Affiliated Cancer Hospital & Institute of Guangzhou Medical University, Guangzhou

516001

RECRUITING

Huizhou Municipal Central Hospital, Huizhou

530000

RECRUITING

The First Affiliated Hospital of Guangxi Medical University, Nanning

537001

RECRUITING

First People People's Hospital of Yulin City, Yulin

537006

RECRUITING

Red Cross Hospital of Yulin City, Yulin

541001

RECRUITING

The Affiliated Hospital of Guilin Medical University, Guilin

543002

RECRUITING

Wuzhou Red Cross Hospital, Wuzhou

545025

RECRUITING

Liuzhou Workers Hospital, Liuzhou

570208

RECRUITING

Huizhou Municipal Central Hospital, Haikou

570311

RECRUITING

The Second Affiliated Hospital of Hainan Medical University, Haikou

570314

RECRUITING

Hainan Cancer Hospital, Haikou

All Listed Sponsors
collaborator

Guangdong Provincial People's Hospital

OTHER

collaborator

Zhejiang Cancer Hospital

OTHER

collaborator

Zhejiang Provincial People's Hospital

OTHER

collaborator

Fujian Cancer Hospital

OTHER_GOV

collaborator

Fujian Provincial Hospital

OTHER

collaborator

Cancer Institute and Hospital, Chinese Academy of Medical Sciences

OTHER

collaborator

The First Affiliated Hospital of Nanchang University

OTHER

collaborator

Second Affiliated Hospital of Nanchang University

OTHER

collaborator

Affiliated Cancer Hospital & Institute of Guangzhou Medical University

OTHER

collaborator

Qingdao Central Hospital

OTHER

collaborator

Huizhou Municipal Central Hospital

OTHER

collaborator

Haikou People's Hospital

OTHER

collaborator

The Second Affiliated Hospital of Hainan Medical University

OTHER

collaborator

Zhejiang Provincial Tongde Hospital

OTHER

collaborator

Guilin Medical University, China

OTHER

collaborator

Liuzhou Workers' Hospital

OTHER_GOV

collaborator

Wuzhou Red Cross Hospital

OTHER

collaborator

Red Cross Hospital of Yulin City

OTHER

collaborator

First People's Hospital of Yulin

OTHER

collaborator

Hainan Cancer Hospital

OTHER

lead

First Affiliated Hospital of Guangxi Medical University

OTHER