The Meaning of Dopaminergic Pathway in Sleep Breathing Disorders.

Each of the patients will undergo polysomnography

In each of the patients blood dopamine level will be measured

Each of the patients will undergo genetical test focusing on selected single nucleotide polymorphisms within genes regulating the concentration of dopamine - the gene responsible for production of the enzyme catechol-O-methyltransferase (COMT) - rs4680 and rs6269 and genes encoding receptors dopamine (DRD1 - rs686, rs5327 and DRD2 - rs1800497).