Effect of Implant Surface Material and Topography on Bone Regeneration.

NACompletedINTERVENTIONAL
Enrollment

12

Participants

Timeline

Start Date

December 1, 2023

Primary Completion Date

January 27, 2025

Study Completion Date

January 27, 2025

Conditions
Dental ImplantGuided Bone RegenerationBiomarkersSaliva
Interventions
COMBINATION_PRODUCT

Zirconia surface implant and guided bone regeneration

"The Straumann® PURE Ceramic Implant System is made from 100 % yttria-stabilized zirconia. Its surface features a topography characterized by macro- and micro-roughness to offer a structure for cell attachment and the osseointegration of this surface has been successfully proven. Owing to the increasing aesthetic standards in the field of implant dentistry and the concerns on sensitivity to titanium, there has been a growing interest towards metal-free implant rehabilitation.~Guided bone regeneration (GBR) will be performed simultaneously with the implant placement with the aim to re-establish the bone contour. A bovine osteoconductive graft (Bio-Oss collagen®, Geistlich, Wolhusen, Switzerland) will be placed on the buccal aspect of the implant and covered with a collagen membrane (Bio-Gide®, Geistlich, Wolhusen, Switzerland)."

COMBINATION_PRODUCT

Hydrophilic titanium surface implant and guided bone regeneration

"The Straumann® Standard Plus (SP) Implant is a Soft Tissue Level Implant with a smooth neck section of 1.8 mm. It has a fundamentally improved hydrophilic surface chemistry (SLActive®) which accelerates the osseointegration process in the early healing phase.~Guided bone regeneration (GBR) will be performed simultaneously with the implant placement with the aim to re-establish the bone contour. A bovine osteoconductive graft (Bio-Oss collagen®, Geistlich, Wolhusen, Switzerland) will be placed on the buccal aspect of the implant and covered with a collagen membrane (Bio-Gide®, Geistlich, Wolhusen, Switzerland)."

Trial Locations (2)

E1 1BB

Barts Health NHS Trust Dental Hospital, London

E1 2AD

Centre for Oral Clinical Research, London

All Listed Sponsors
collaborator

University of Zurich

OTHER

lead

Queen Mary University of London

OTHER

NCT05890469 - Effect of Implant Surface Material and Topography on Bone Regeneration. | Biotech Hunter | Biotech Hunter