NCT05887219View on ClinicalTrials.gov

Comparison of Azelaic Acid 20 % Cream Versus Hydroquinone 4% Cream as an Adjuvant to Oral Tranexamic Acid in Melasma

PHASE1CompletedINTERVENTIONAL
Enrollment

50

Participants

Timeline

Start Date

November 1, 2022

Primary Completion Date

April 30, 2023

Study Completion Date

April 30, 2023

Conditions
Melasma
Interventions
DRUG

Group A 4 % Hydroquinone Cream Topically and Oral Tranexamic Acid

Group A was managed with 4% hydroquinone cream as an adjuvant to oral tranexamic acid (250 mg twice daily) for 6 months

DRUG

Group B Azelaic Acid 20 % Cream for 6 months

Group B was managed with topical 20% azelaic acid (daily at night) for six months.

Trial Locations (1)

22010

Zahra Nigar, Abbottabad

All Listed Sponsors
lead

Combined Military Hospital Abbottabad

OTHER