Exercise vs. Topical Diclofenac vs. PRP

NACompletedINTERVENTIONAL
Enrollment

82

Participants

Timeline

Start Date

March 20, 2024

Primary Completion Date

March 18, 2025

Study Completion Date

May 18, 2025

Conditions
Gonarthrosis
Interventions
OTHER

Exercise

The first 3 weeks of the exercise program will include range of motion exercises, isometric and isotonic strengthening exercises for the muscles around the knee and hip, and stretching exercises. In the following 3 weeks, resistance strengthening exercises and closed kinetic chain exercises will be added to the program.

OTHER

Topical Diclofenac

They will apply it around the knee joint 4 days a week, 2 times a day (every 12 hours), morning and evening for 6 weeks.

OTHER

Platelet-Rich-Plasma (PRP)

8 ml of blood will be taken from each patient in tubes containing 0.9 ml of 3.2% sodium citrate. Swing-out rotor (open-swing type) will be placed in the centrifuge with the tubes facing each other. After centrifugation, 2.5 cc of PRP product will be collected from each tube and the resulting PRP will be administered to patients by injection under sterile conditions.

Trial Locations (1)

34500

Istanbul University-Cerrahpasa, Istanbul

All Listed Sponsors
lead

Istanbul University - Cerrahpasa

OTHER

NCT05877027 - Exercise vs. Topical Diclofenac vs. PRP | Biotech Hunter | Biotech Hunter