uTRACT Jelmyto Registry: A Registry of Patients With Upper Tract Urothelial Cancer (UTUC) Treated With Jelmyto

RecruitingOBSERVATIONAL
Enrollment

400

Participants

Timeline

Start Date

November 17, 2023

Primary Completion Date

April 30, 2026

Study Completion Date

January 31, 2028

Conditions
Urothelial CarcinomaUrothelial Carcinoma RecurrentUrothelial Carcinoma UreterUrothelial Carcinoma Ureter RecurrentUrothelial Cancer of Renal PelvisUrothelial Carcinoma of the Renal Pelvis and UreterCarcinoma, Transitional CellTransitional Cell Carcinoma of Renal Pelvis
Interventions
DRUG

Jelmyto (mitomycin) for pyelocalyceal solution

"The dose of Jelmyto to be instilled is 4 mg per mL via ureteral catheter or a nephrostomy tube, with total instillation volume based on volumetric measurements using pyelography, not to exceed 15 mL (60 mg of mitomycin).~Instill Jelmyto once weekly for six weeks. For patients with a complete response 3 months after Jelmyto initiation, Jelmyto instillations may be administered once a month for a maximum of 11 additional instillations."

Trial Locations (22)

10016

RECRUITING

NYU Grossman School of Medicine, New York

11042

RECRUITING

The Feinstein Institutes for Medical Research, Lake Success

13210

RECRUITING

SUNY Upstate, Syracuse

21204

RECRUITING

Chesapeake Urology, Baltimore

21287

RECRUITING

Johns Hopkins Medical Center, Baltimore

27599

RECRUITING

The University of North Carolina Chapel Hill, Chapel Hill

29425

RECRUITING

Medical University of South Carolina, Charleston

32610

RECRUITING

University of Florida, Gainesville

33140

RECRUITING

Mount Sinai Medical Center of Florida, Inc., Miami

33612

RECRUITING

H. Lee Moffitt Cancer Center and Research Institute Hospital, Inc., Tampa

43202

RECRUITING

Ohio State University, Columbus

46202

RECRUITING

Indiana University, Indianapolis

48109

RECRUITING

University of Michigan, Ann Arbor

52242

RECRUITING

The State University of Iowa, Iowa City

60611

RECRUITING

Northwestern University, Chicago

65211

RECRUITING

University of Missouri, Columbia

75390

RECRUITING

UT Southwestern Medical Center, Dallas

77030

RECRUITING

The University of Texas M.D. Anderson Cancer Center, Houston

90404

RECRUITING

Providence St. Johns Health Center, Santa Monica

02114

RECRUITING

Mass General Hospital (MGH), Boston

02115

RECRUITING

The Brigham and Womens Hospital, Boston

08903

RECRUITING

Rutgers, New Brunswick

All Listed Sponsors
lead

UroGen Pharma Ltd.

INDUSTRY