NCT05873439View on ClinicalTrials.gov

Genomically Guided Radiation Dose Personalization in Locally Advanced NSCLC

EARLY_PHASE1Active, not recruitingINTERVENTIONAL
Enrollment

3

Participants

Timeline

Start Date

May 25, 2023

Primary Completion Date

November 29, 2023

Study Completion Date

October 31, 2026

Conditions
Nonsmall Cell Lung CancerNonsmall Cell Lung Cancer, Stage IINonsmall Cell Lung Cancer Stage IIIUnresectable Non-Small Cell Lung Carcinoma
Interventions
RADIATION

Genomically Guided Radiation Therapy (RT)

Based on the Radiosensitivity Index (RSI) from testing participants tumor sample, participants will receive either standard dose radiation therapy, which is a strength 60Gy or up to 81Gy strength. Radiation treatment is administered 5 days per week for approximately 6 weeks.

Trial Locations (1)

33612

Moffitt Cancer Center, Tampa

All Listed Sponsors
lead

H. Lee Moffitt Cancer Center and Research Institute

OTHER