Beta-blockers or Placebo for Primary Prophylaxis (BOPPP) of Oesophageal Varices Trial.

PHASE4RecruitingINTERVENTIONAL
Enrollment

1,200

Participants

Timeline

Start Date

June 1, 2019

Primary Completion Date

December 31, 2026

Study Completion Date

December 31, 2026

Conditions
Cirrhosis, LiverPortal HypertensionVariceal HemorrhageVarices, Esophageal
Interventions
DRUG

Carvedilol

Carvedilol, sold under the brand name Coreg among others, is a medication used to treat high blood pressure, congestive heart failure, and left ventricular dysfunction in people who are otherwise stable. For high blood pressure, it is generally a second-line treatment. It is taken by mouth.

DRUG

Placebo

Placebo

Trial Locations (1)

SE5 9RS

RECRUITING

King's College Hospital, London

All Listed Sponsors
collaborator

King's College London

OTHER

collaborator

Cardiff University

OTHER

collaborator

Brighton and Sussex University Hospitals NHS Trust

OTHER

lead

King's College Hospital NHS Trust

OTHER