Efficacy and Safety of SPH4336 in Combination With Endocrine Therapy in Breast Cancer Patients With Brain Metastases.

PHASE2RecruitingINTERVENTIONAL
Enrollment

52

Participants

Timeline

Start Date

September 19, 2023

Primary Completion Date

December 31, 2025

Study Completion Date

December 31, 2025

Conditions
Breast Cancer Brain Metastases
Interventions
DRUG

SPH4336 Tablets

SPH4336 Tablets :Administered by oral; Letrozole tablets:Administered by oral; Fulvestrant injection:Administered by intravenous infusion; Exemestane:Administered by oral.

Trial Locations (25)

100730

RECRUITING

Peking Union Medical College Hospital, Beijing

130012

RECRUITING

Jilin Cancer Hospital, Changchun

130061

RECRUITING

The first hospital of Jilin University, Changchun

150081

RECRUITING

Harbin Medical University cancer Hospital, Harbin

210029

RECRUITING

Jiangsu Province Hospital, Nanjing

230002

RECRUITING

Anhui provincial hospital, Hefei

230022

RECRUITING

The First Affiliated Hospital of Anhui Medical University, Hefei

310005

RECRUITING

Zhejiang cancer Hospital, Hangzhou

404031

RECRUITING

Chongqing University Three Gorges Hospital, Chongqing

441021

RECRUITING

Xiangyang Central Hospital, Xiangyang

450052

RECRUITING

The First Affiliated Hospital of Henan University of Science and Technology, Luoyang

455001

RECRUITING

Anyang Cancer Hospital, Anyang

510060

RECRUITING

Affiliated Cancer Hospital, Sun Yat-sen University, Guangzhou

545026

RECRUITING

Liuzhou people's Hospital, Liuzhou

641199

RECRUITING

The second people's hospital of neijiang, Neijiang

750003

RECRUITING

General Hospital of Ningxia Medical University, Yinchuan

830054

RECRUITING

Cancer Hospital of Xinjiang Medical University, Ürümqi

050011

RECRUITING

The Fourth Hospital of Hebei Medical University, Shijiazhuang

Unknown

RECRUITING

Beijing Cancer Hospital, Beijing

RECRUITING

The First Affiliated Hospital of Bengbu Medical College, Bengbu

RECRUITING

Guangxi Medical University Cancer Hospital & Guangxi Cancer Institute, Nanning

RECRUITING

Tianjin Medical University Cancer Institute & Hospital, Tianjin

RECRUITING

Union Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan

RECRUITING

Xi'An International Medical Cancer Hospital, Xi'an

RECRUITING

Henan Cancer Hospital, Zhengzhou

All Listed Sponsors
lead

Shanghai Pharmaceuticals Holding Co., Ltd

INDUSTRY