NCT05870150View on ClinicalTrials.gov

Challenge Non-Typhoidal Salmonella (CHANTS) Study

NAActive, not recruitingINTERVENTIONAL
Enrollment

80

Participants

Timeline

Start Date

August 31, 2023

Primary Completion Date

February 28, 2026

Study Completion Date

February 28, 2026

Conditions
Salmonella InfectionsSalmonella TyphimuriumNon-typhoidal Salmonella (NTS)Invasive Non-Typhoidal Salmonella DiseaseCommunicable DiseaseInfections, BacterialEnteric Fever (Not Typhoid)Gastroenteritis
Interventions
BIOLOGICAL

Salmonella Typhimurium

Salmonella Typhimurium oral challenge. Dose-escalating (1-5x10\^3 CFU, 1-5x10\^4 CFU, 1-5x10\^5 CFU, 1-5x10\^6 CFU)

Trial Locations (1)

W2 1NY

Imperial College London, London

All Listed Sponsors
collaborator

University of Oxford

OTHER

collaborator

University of Liverpool

OTHER

collaborator

PATH

OTHER

collaborator

Imperial College London

OTHER

lead

Imperial College Healthcare NHS Trust

OTHER