159
Participants
Start Date
May 1, 2023
Primary Completion Date
October 4, 2024
Study Completion Date
June 16, 2025
Neflamapimod
Neflamapimod is a highly specific inhibitor of the intra-cellular enzyme mitogen-activated protein kinase14 (p38α) provided in 40mg capsules
Placebo
Placebo is a capsule that looks just like neflamapimod but without the active ingredients
Brain Research Center - Amsterdam, Amsterdam
Brain Research Center - Den Bosch, 's-Hertogenbosch
Brain Research Center - Zwolle, Zwolle
Columbia University - Taub Institute/Neurology Dept, New York
Georgetown Univ Hospital - Dept of Neurology, Washington D.C.
Johns Hopkins School of Medicine - Dept of Neurology, Baltimore
Sana Research, Arlington
Virginia Commonwealth University - Parkinson's and Movement Disorders Center, Richmond
University of North Carolina - Dept of Neurology, Chapel Hill
Panhandle Research and Medical Clinic, Pensacola
AdventHealth Neuroscience Research, Orlando
ClinCloud, Melbourne
JEM Research Institute, Lake Worth
Ohio State University - Dept of Neurology, Columbus
Cleveland Clinic - Center for Brain Health, Cleveland
NeuroScience Research Center, Canton
Mayo Clinic - Alzheimer's Disease Research Center, Rochester
University of Kansas Medical Center, Kansas City
University of Nebraska Medical Center - Dept of Neurological Sciences, Omaha
Tandem Clinical Research, Marrero
Houston Methodist Hospital - Stanley Appel Neurology Dept, Houston
University of Colorado - Dept of Neurology, Aurora
Barrow Neurological Institute, Phoenix
Banner Sun Health Research Institute, Sun City
Banner Alzheimer's Institute - Edson Family Lewy Body Dementia Center, Tucson
Cleveland Clinic - Lou Ruvo Center for Brain Health, Las Vegas
SC3 Research Group, Pasadena
UCSD Health Sciences - Movement Disorders Center, La Jolla
Hoag Memorial Hospital Presbyterian, Newport Beach
Stanford Neuroscience Health Center, Palo Alto
Center for Cognitive Health, Portland
Mass General Hospital/Harvard Medical School - Dept of Neurology, Charlestown
Belfast Health & Social Care Trust, Belfast
Cambridgeshire and Peterborough NHS Foundation Trust, Fulbourn Hospital - Windsor Research Unit, Cambridge
South London and Maudsley NHS Foundation Trust, London
Re:Cognition Health, London
University College London (UCL) Clinical Research Facility, University College London Hospitals NHS Foundation Trust, London
Campus Ageing Research Unit (CARU) - Newcastle upon Tyne, CNTW NHS Foundation Trust, Newcastle upon Tyne
Cornwall Partnership NHS Foundation Trust (University of Exeter), Redruth
Memory Assessment and Research Centre (MARC) - Moorgreen Hospital, Southampton
Lead Sponsor
Collaborators (2)
National Institute on Aging (NIA)
NIH
Worldwide Clinical Trials
OTHER
CervoMed, Inc
UNKNOWN
EIP Pharma Inc
INDUSTRY