24
Participants
Start Date
October 23, 2023
Primary Completion Date
December 31, 2025
Study Completion Date
December 31, 2025
Cryoneurolysis
Cryoneurolysis will be performed on the intercostal nerve associated with each fractured rib using a handheld cryoneurolysis machine (Iovera). Cryoneurolysis will consist of two 103 second cycles (includes cooling, ice ball formation and warming time) per rib fracture level. Ultrasound guidance will be used to identify appropriate rib fracture levels and to target the device tip in real time. All participants will also receive standard multimodal analgesia and ESP catheter infusion.
Sham Cryoneurolysis
Participants in the control group will receive sham CN (i.e., application of device without skin puncture or activation of unit) to maintain participant blinding. All participants will also receive standard multimodal analgesia and ESP catheter infusion.
RECRUITING
Sunnybrook Health Sciences Centre, Toronto
Sunnybrook Health Sciences Centre
OTHER