Comparison of Hemodynamic Stability During Anesthesia Using Remimazolam and Sevoflurane in Minimally Invasive AVR

NACompletedINTERVENTIONAL
Enrollment

64

Participants

Timeline

Start Date

June 29, 2023

Primary Completion Date

June 10, 2025

Study Completion Date

June 10, 2025

Conditions
Aortic Valve StenosisRemimazolam
Interventions
DRUG

Remimazolam besylate

During induction, patients allocated to the remimazolam group will receive remimazolam 6mg/kg/h with remifentanil TCI 1\~4 nanogram/mL. After patient loses consciousness, anesthesia will be maintained with remimazolam 1-2mg/kg/h combied with remifetanil.

DRUG

Propofol/ Sevoflurane

During induction, patients allocated to the P/S group will receive propofol 1% 1-2mg/kg with remifentanil TCI 1\~4 nanogram/mL. After patient loses consciousness, anesthesia will be maintained with sevoflurane and remifentanil.

Trial Locations (1)

50612

Pusan National University Yangsan Hospital, Yangsan

All Listed Sponsors
lead

Pusan National University Yangsan Hospital

OTHER