Mechanisms of Neurodynamic Treatments

NARecruitingINTERVENTIONAL
Enrollment

108

Participants

Timeline

Start Date

May 17, 2023

Primary Completion Date

February 28, 2025

Study Completion Date

April 1, 2026

Conditions
Carpal Tunnel SyndromeNeurodynamic TreatmentNerve MobilisationDiffusion MRIPhysiotherapyMechanistic Trial
Interventions
OTHER

Neurodynamic exercises

The neurodynamic exercises will consist of a home-based exercise programme performed over a period of 6 weeks. Patients will attend a single session with an investigator who will instruct them the home exercise programme consisting of nerve and tendon gliding exercises which will be adjusted with pre-specified progressions over the 6 weeks intervention period. Patients will receive a leaflet and a video link detailing these exercises.

DRUG

Steroid injection (Depomedrone 40mg)

Steroid injection (Depomedrone 40mg) into the carpal tunnel as per standard practice in patients with carpal tunnel syndrome

OTHER

Advice

Group receiving advice but no additional treatment

Trial Locations (1)

OX3 9DU

RECRUITING

Nuffield Department of Clinical Neurosciences, University of Oxford, Oxford

All Listed Sponsors
collaborator

Wellcome Trust

OTHER

lead

University of Oxford

OTHER