NCT05857774View on ClinicalTrials.gov

Respiratory Muscle Structure and Function in Mechanically Ventilated Patients and Long-term Outcomes

RecruitingOBSERVATIONAL
Enrollment

230

Participants

Timeline

Start Date

April 27, 2023

Primary Completion Date

December 31, 2025

Study Completion Date

June 30, 2026

Conditions
Mechanical Ventilation ComplicationDiaphragm InjuryLung InjuryRespiratory InsufficiencyAbdominal Muscle Strained
Interventions
OTHER

Sonographic measurements

Diaphragm thickness, diaphragm tidal thickening fraction, abdominal muscle thickness, rectus femoris cross-sectional area, maximal diaphragm thickening fraction, abdominal muscle thickening fraction

OTHER

Physiological measurements

Airway occlusion pressure, maximal inspiratory pressure, muscle research council score

OTHER

Biological measurements

Skeletal troponin-I

Trial Locations (1)

M5G 2N2

RECRUITING

Toronto General Hospital, Toronto

All Listed Sponsors
lead

University Health Network, Toronto

OTHER