Exercise Response in Humans With Obesity

Measurement of whole-body fitness level. Walking or running on a treadmill and breathing into a machine that measures oxygen level during test. Heart rhythm is continuously monitored during exercise using an electrocardiogram (ECG).

Measure the strength of leg muscles by kicking against a machine with resistance.

Body composition measurement.

Obtain a small piece of muscles from the upper part of the legs

Fat sample taken from abdomen

Measured by indirect calorimetry. Measures how much energy the body uses at rest by placing a special plastic dome over the head while resting quietly for 30 minutes. Measures oxygen breathed in and carbon dioxide breathed out.

MRI on upper leg to look at fat and muscle