NCT05855200View on ClinicalTrials.gov

Study of Perioperative Dostarlimab in Participants With Untreated T4N0 or Stage III dMMR/MSI-H Resectable Colon Cancer

PHASE3RecruitingINTERVENTIONAL
Enrollment

811

Participants

Timeline

Start Date

August 1, 2023

Primary Completion Date

March 19, 2029

Study Completion Date

March 27, 2031

Conditions
Colonic NeoplasmsNeoplasms, Colon
Interventions
BIOLOGICAL

Dostarlimab

Dostarlimab will be administered.

DRUG

CAPEOX

CAPEOX will be administered.

DRUG

FOLFOX

FOLFOX will be administered.

Trial Locations (253)

100

RECRUITING

GSK Investigational Site, Taipei

333

RECRUITING

GSK Investigational Site, Taoyuan District

704

RECRUITING

GSK Investigational Site, Tainan City

833

RECRUITING

GSK Investigational Site, Kaohsiung City

1070

RECRUITING

GSK Investigational Site, Brussels

1093

RECRUITING

GSK Investigational Site, Buenos Aires

1200

RECRUITING

GSK Investigational Site, Brussels

1474

RECRUITING

GSK Investigational Site, Lrenskog

2065

WITHDRAWN

GSK Investigational Site, St Leonards

2298

RECRUITING

GSK Investigational Site, Newcastle

2650

RECRUITING

GSK Investigational Site, Edegem

3000

RECRUITING

GSK Investigational Site, Leuven

3004

WITHDRAWN

GSK Investigational Site, Melbourne

3084

RECRUITING

GSK Investigational Site, Heidelberg

4000

RECRUITING

GSK Investigational Site, Liège

4011

RECRUITING

GSK Investigational Site, Stavanger

4102

RECRUITING

GSK Investigational Site, Woolangabba

4604

RECRUITING

GSK Investigational Site, Kristiansand

5000

RECRUITING

GSK Investigational Site, Córdoba

5021

RECRUITING

GSK Investigational Site, Bergen

7600

RECRUITING

GSK Investigational Site, Mar del Plata

8800

RECRUITING

GSK Investigational Site, Roeselare

9000

RECRUITING

GSK Investigational Site, Ghent

9019

WITHDRAWN

GSK Investigational Site, Tromsø

9300

RECRUITING

GSK Investigational Site, Aalst

10028

RECRUITING

GSK Investigational Site, New York

10461

RECRUITING

GSK Investigational Site, The Bronx

10469

RECRUITING

GSK Investigational Site, New York

11042

RECRUITING

GSK Investigational Site, New York

11219

RECRUITING

GSK Investigational Site, Stockholm

11312

RECRUITING

GSK Investigational Site, Tallinn

11528

COMPLETED

GSK Investigational Site, Athens

11883

RECRUITING

GSK Investigational Site, Stockholm

11967

RECRUITING

GSK Investigational Site, New York

13353

RECRUITING

GSK Investigational Site, Berlin

13385

RECRUITING

GSK Investigational Site, Marseille

13419

RECRUITING

GSK Investigational Site, Tallinn

14000

RECRUITING

GSK Investigational Site, DF

14004

RECRUITING

GSK Investigational Site, Córdoba

15212

RECRUITING

GSK Investigational Site, Pittsburgh

16132

RECRUITING

GSK Investigational Site, Genova

18014

RECRUITING

GSK Investigational Site, Granada

20010

WITHDRAWN

GSK Investigational Site, Washington D.C.

20080

RECRUITING

GSK Investigational Site, Donostia / San Sebastian

20089

RECRUITING

GSK Investigational Site, Rozzano MI

20162

RECRUITING

GSK Investigational Site, Milan

20502

RECRUITING

GSK Investigational Site, Malmo

20521

RECRUITING

GSK Investigational Site, Turku

20817

RECRUITING

GSK Investigational Site, Bethesda

22010

RECRUITING

GSK Investigational Site, Tijuana

23007

RECRUITING

GSK Investigational Site, Jaén

23229

RECRUITING

GSK Investigational Site, Richmond

23562

RECRUITING

GSK Investigational Site, Lübeck

27710

RECRUITING

GSK Investigational Site, Durham

28006

RECRUITING

GSK Investigational Site, Madrid

28009

RECRUITING

GSK Investigational Site, Madrid

28034

RECRUITING

GSK Investigational Site, Madrid

28040

RECRUITING

GSK Investigational Site, Madrid

RECRUITING

GSK Investigational Site, Madrid

28041

RECRUITING

GSK Investigational Site, Madrid

28046

RECRUITING

GSK Investigational Site, Madrid

28050

RECRUITING

GSK Investigational Site, Madrid

28222

RECRUITING

GSK Investigational Site, Madrid

29010

RECRUITING

GSK Investigational Site, Málaga

30060

WITHDRAWN

GSK Investigational Site, Marietta

31008

RECRUITING

GSK Investigational Site, Pamplona

31059

RECRUITING

GSK Investigational Site, Toulouse

33011

RECRUITING

GSK Investigational Site, Oviedo

33064

WITHDRAWN

GSK Investigational Site, Deerfield Beach

33316

WITHDRAWN

GSK Investigational Site, Fort Lauderdale

33520

RECRUITING

GSK Investigational Site, Tampere

33604

RECRUITING

GSK Investigational Site, Pessac

34722

RECRUITING

GSK Investigational Site, Istanbul

35016

RECRUITING

GSK Investigational Site, Las Palmas de Gran Canar

35042

RECRUITING

GSK Investigational Site, Rennes

35128

RECRUITING

GSK Investigational Site, Padua

39011

RECRUITING

GSK Investigational Site, Santander

40123

RECRUITING

GSK Investigational Site, Reggio Emilia

40225

RECRUITING

GSK Investigational Site, Düsseldorf

40503

RECRUITING

GSK Investigational Site, Lexington

41013

RECRUITING

GSK Investigational Site, Seville

41404

RECRUITING

GSK Investigational Site, Daegu

42270

RECRUITING

GSK Investigational Site, Saint-Priest-en-Jarez

44093

RECRUITING

GSK Investigational Site, Nantes

44111

WITHDRAWN

GSK Investigational Site, Cleveland

44142

WITHDRAWN

GSK Investigational Site, Cleveland

44196

WITHDRAWN

GSK Investigational Site, Cleveland

44280

RECRUITING

GSK Investigational Site, Guadalajara

44304

RECRUITING

GSK Investigational Site, Akron

44650

RECRUITING

GSK Investigational Site, Guadalajara

45220

RECRUITING

GSK Investigational Site, Cincinnati

46009

RECRUITING

GSK Investigational Site, Valencia

46010

RECRUITING

GSK Investigational Site, Valencia

46014

RECRUITING

GSK Investigational Site, Valencia

48109

WITHDRAWN

GSK Investigational Site, Ann Arbor

48202

RECRUITING

GSK Investigational Site, Detroit

48903

RECRUITING

GSK Investigational Site, BaracaldoVizcaya

50009

RECRUITING

GSK Investigational Site, Zaragoza

50501

RECRUITING

GSK Investigational Site, Tartu

54639

COMPLETED

GSK Investigational Site, Thessaloniki

54911

RECRUITING

GSK Investigational Site, Appleton

55455

RECRUITING

GSK Investigational Site, Minneapolis

56126

RECRUITING

GSK Investigational Site, Pisa

57078

RECRUITING

GSK Investigational Site, Sioux Falls

57105

RECRUITING

GSK Investigational Site, Sioux Falls

57401

RECRUITING

GSK Investigational Site, Sioux Falls

57501

RECRUITING

GSK Investigational Site, Sioux Falls

60126

RECRUITING

GSK Investigational Site, Naperville

60488

RECRUITING

GSK Investigational Site, Frankfurt

60540

RECRUITING

GSK Investigational Site, Naperville

60611

RECRUITING

GSK Investigational Site, Chicago

60612

RECRUITING

GSK Investigational Site, Chicago

60637

RECRUITING

GSK Investigational Site, Chicago

63128

RECRUITING

GSK Investigational Site, St Louis

63141

RECRUITING

GSK Investigational Site, St Louis

63349

RECRUITING

GSK Investigational Site, Eskilstuna

64804

RECRUITING

GSK Investigational Site, Joplin

66205

RECRUITING

GSK Investigational Site, Westwood

66220

RECRUITING

GSK Investigational Site, San Pedro Garza García

68020

RECRUITING

GSK Investigational Site, Oaxaca City

68130

RECRUITING

GSK Investigational Site, Omaha

68167

RECRUITING

GSK Investigational Site, Mannheim

68198

RECRUITING

GSK Investigational Site, Omaha

68803

RECRUITING

GSK Investigational Site, Grand Island

69008

RECRUITING

GSK Investigational Site, Lyon

70809

RECRUITING

GSK Investigational Site, Baton Rouge

73104

RECRUITING

GSK Investigational Site, Oklahoma City

73120

RECRUITING

GSK Investigational Site, Oklahoma City

75015

RECRUITING

GSK Investigational Site, Paris

75235

RECRUITING

GSK Investigational Site, Dallas

75390

RECRUITING

GSK Investigational Site, Dallas

76000

COMPLETED

GSK Investigational Site, Rouen

80131

RECRUITING

GSK Investigational Site, Napoli

81377

RECRUITING

GSK Investigational Site, München

81737

RECRUITING

GSK Investigational Site, München

85715

RECRUITING

GSK Investigational Site, Tucson

90027

RECRUITING

GSK Investigational Site, Los Angeles

92150

RECRUITING

GSK Investigational Site, Suresnes

94805

RECRUITING

GSK Investigational Site, Villejuif

100036

RECRUITING

GSK Investigational Site, Beijing

100083

RECRUITING

GSK Investigational Site, Beijing

100730

RECRUITING

GSK Investigational Site, Beijing

130021

RECRUITING

GSK Investigational Site, Changchun

150000

RECRUITING

GSK Investigational Site, Harbin

200032

RECRUITING

GSK Investigational Site, Shanghai

RECRUITING

GSK Investigational Site, Shanghai

225001

RECRUITING

GSK Investigational Site, Yangzhou

250117

RECRUITING

GSK Investigational Site, Jinan

300000

RECRUITING

GSK Investigational Site, Tianjin

310016

RECRUITING

GSK Investigational Site, Hangzhou

310022

RECRUITING

GSK Investigational Site, Hangzhou

311100

RECRUITING

GSK Investigational Site, Hangzhou

330006

RECRUITING

GSK Investigational Site, Nanchang

330029

RECRUITING

GSK Investigational Site, Nanchang

361004

RECRUITING

GSK Investigational Site, Xiamen

400042

RECRUITING

GSK Investigational Site, Chongqing

RECRUITING

GSK Investigational Site, Chongqing

430030

RECRUITING

GSK Investigational Site, Wuhan

450052

RECRUITING

GSK Investigational Site, Zhengzhou

463712

RECRUITING

GSK Investigational Site, Gyeonggi-do

510060

RECRUITING

GSK Investigational Site, Guangzhou

510655

RECRUITING

GSK Investigational Site, Guangzhou

514700

RECRUITING

GSK Investigational Site, Meizhou

518036

RECRUITING

GSK Investigational Site, Shenzhen

610041

RECRUITING

GSK Investigational Site, Chengdu

650106

RECRUITING

GSK Investigational Site, Kunming

06520

RECRUITING

GSK Investigational Site, New Haven

04206

WITHDRAWN

GSK Investigational Site, Louisville

03756

RECRUITING

GSK Investigational Site, Lebanon

C1180AAX

RECRUITING

GSK Investigational Site, Buenos Aires

C1181ACH

RECRUITING

GSK Investigational Site, Buenos Aires

C1426ANZ

RECRUITING

GSK Investigational Site, Capital Federal

C1431FWO

RECRUITING

GSK Investigational Site, Ciudad Autonoma de Buenos Aire

S2002

RECRUITING

GSK Investigational Site, Rosario

T4000IHE

RECRUITING

GSK Investigational Site, San Miguel de Tucumán

S3000FUJ

RECRUITING

GSK Investigational Site, Santa Fe

14784-400

RECRUITING

GSK Investigational Site, Barretos

88501-001

RECRUITING

GSK Investigational Site, Lages

59075-740

RECRUITING

GSK Investigational Site, Natal

90610-000

RECRUITING

GSK Investigational Site, Porto Alegre

40414-120

RECRUITING

GSK Investigational Site, Salvador

15090-000

RECRUITING

GSK Investigational Site, São José do Rio Preto

01509-010

RECRUITING

GSK Investigational Site, São Paulo

04312903

RECRUITING

GSK Investigational Site, São Paulo

64049-200

RECRUITING

GSK Investigational Site, Teresina

29043-260

RECRUITING

GSK Investigational Site, Vitória

T6G 1Z2

RECRUITING

GSK Investigational Site, Edmonton

B3H 1V7

RECRUITING

GSK Investigational Site, Halifax

K1H 8L6

RECRUITING

GSK Investigational Site, Ottawa

M5G 2M9

RECRUITING

GSK Investigational Site, Toronto

H4A 3J1

RECRUITING

GSK Investigational Site, Montreal

Unknown

RECRUITING

GSK Investigational Site, Hangzhou

RECRUITING

GSK Investigational Site, Punta Pacifica Panama City Panama

RECRUITING

GSK Investigational Site, Ankara

030013

RECRUITING

GSK Investigational Site, Taiyuan

00029

RECRUITING

GSK Investigational Site, Helsinki

06120

WITHDRAWN

GSK Investigational Site, Halle

570 10

COMPLETED

GSK Investigational Site, Thessaloniki

09042

RECRUITING

GSK Investigational Site, Cagliari

00152

RECRUITING

GSK Investigational Site, Roma

00168

RECRUITING

GSK Investigational Site, Roma

464-8681

RECRUITING

GSK Investigational Site, Aichi

277-8577

RECRUITING

GSK Investigational Site, Chiba

812-8582

RECRUITING

GSK Investigational Site, Fukuoka

060-8648

RECRUITING

GSK Investigational Site, Hokkaido

650-0047

WITHDRAWN

GSK Investigational Site, Hyōgo

309-1793

RECRUITING

GSK Investigational Site, Ibaraki

216-8511

RECRUITING

GSK Investigational Site, Kanagawa

232-0024

RECRUITING

GSK Investigational Site, Kanagawa

606-8507

RECRUITING

GSK Investigational Site, Kyoto

710-8602

RECRUITING

GSK Investigational Site, Okayama

540-0006

RECRUITING

GSK Investigational Site, Osaka

541-8567

RECRUITING

GSK Investigational Site, Osaka

558-8558

RECRUITING

GSK Investigational Site, Osaka

565-0871

RECRUITING

GSK Investigational Site, Osaka

573-1191

RECRUITING

GSK Investigational Site, Osaka

411-8777

RECRUITING

GSK Investigational Site, Shizuoka

104-0045

RECRUITING

GSK Investigational Site, Tokyo

135-8550

RECRUITING

GSK Investigational Site, Tokyo

03100

RECRUITING

GSK Investigational Site, Mexico City

4818 CK

RECRUITING

GSK Investigational Site, Breda

6229 HX

RECRUITING

GSK Investigational Site, Maastricht

6525 GA

RECRUITING

GSK Investigational Site, Nijmegen

3584 CX

RECRUITING

GSK Investigational Site, Utrecht

0407

RECRUITING

GSK Investigational Site, Oslo

2805-267

RECRUITING

GSK Investigational Site, Almada

3000-075

RECRUITING

GSK Investigational Site, Coimbra

1649-035

RECRUITING

GSK Investigational Site, Lisbon

03722

RECRUITING

GSK Investigational Site, Seoul

06351

RECRUITING

GSK Investigational Site, Seoul

06591

RECRUITING

GSK Investigational Site, Seoul

138-736

RECRUITING

GSK Investigational Site, Seoul

06080

RECRUITING

GSK Investigational Site, Badajoz

08026

RECRUITING

GSK Investigational Site, Barcelona

08035

RECRUITING

GSK Investigational Site, Barcelona

08036

RECRUITING

GSK Investigational Site, Barcelona

03203

RECRUITING

GSK Investigational Site, Elche Alicante

08908

RECRUITING

GSK Investigational Site, L'Hospitalet de Llobrega

SE-413 45

RECRUITING

GSK Investigational Site, Gothenburg

SE-581 85

RECRUITING

GSK Investigational Site, Linköping

SE-751 85

RECRUITING

GSK Investigational Site, Uppsala

06010

RECRUITING

GSK Investigational Site, Ankara

06230

RECRUITING

GSK Investigational Site, Ankara

B9 5SS

RECRUITING

GSK Investigational Site, Birmingham

CM1 7ET

RECRUITING

GSK Investigational Site, Chelmsford

GL53 7AN

RECRUITING

GSK Investigational Site, Cheltenham

EH4 2XU

RECRUITING

GSK Investigational Site, Edinburgh

HU16 5JQ

RECRUITING

GSK Investigational Site, Hull

LS9 7TF

RECRUITING

GSK Investigational Site, Leeds West Yorkshire

NW3 2QG

RECRUITING

GSK Investigational Site, London

SW3 6JJ

RECRUITING

GSK Investigational Site, London

M20 4BX

RECRUITING

GSK Investigational Site, Manchester

SM2 5PT

RECRUITING

GSK Investigational Site, Sutton

Sponsors

Lead Sponsor

GlaxoSmithKline
All Listed Sponsors
lead

GlaxoSmithKline

INDUSTRY

NCT05855200 - Study of Perioperative Dostarlimab in Participants With Untreated T4N0 or Stage III dMMR/MSI-H Resectable Colon Cancer | Biotech Hunter | Biotech Hunter