Hyperinsulinemia in Prediabetes Mediated by Interleukin-1β

PHASE2CompletedINTERVENTIONAL
Enrollment

20

Participants

Timeline

Start Date

June 15, 2023

Primary Completion Date

May 17, 2024

Study Completion Date

May 17, 2024

Conditions
HyperinsulinemiaPreDiabetes
Interventions
DRUG

Anakinra

Subjects receive an s.c. injection of 100 mg Anakinra on the evening before and on the respective study day 60 minutes before ingestion of the mixed-meal

DRUG

Placebo

0.67 ml of s.c. injection of saline will be taken on the evening before and on the respective study day 60 minutes before ingestion of the mixed-meal

Trial Locations (1)

4031

University Hospital Basel, Basel

All Listed Sponsors
lead

University Hospital, Basel, Switzerland

OTHER