200
Participants
Start Date
July 20, 2023
Primary Completion Date
September 30, 2024
Study Completion Date
January 30, 2025
Vitis Vinifera seed extract medication plus therapeutic lifestyle change
Administer 150mg of Vitis Vinifera seed extract (Entelon®) orally twice a day
Therapeutic lifestyle change only
Implementing TLCs is a critical component of a comprehensive treatment plan for varicose veins. A key aspect of TLCs is the optimization of postural habits. Patients are advised to avoid extended sitting or standing periods, which exert additional pressure on the venous system in the lower extremities and exacerbate venous insufficiency. During rest periods, elevating the legs closer to the heart is recommended because this simple yet effective adjustment promotes venous return and reduces the gravitational burden on the venous valves of the legs. The use of graduated compression stockings during waking hours is another therapeutic lifestyle intervention that is often prescribed for patients with varicose veins. Additional TLCs include maintaining optimal body weight and engaging in regular physical exercise Walking or cycling are often recommended because of their effectiveness in promoting lower limb venous return.
Yongin Severance Hospitall, Yonsei University College of Medicine, Yongin
Yonsei University
OTHER