78
Participants
Start Date
May 20, 2023
Primary Completion Date
November 30, 2023
Study Completion Date
November 30, 2023
Dexmedetomidine Hydrochloride 'Precedex' combined with
Dexmedetomidine Hydrochloride which is an Alfa 2 receptor agonist
Lumbar epidural analgesia with Bupivacaine 0.25% 'Sunnypivacaine'
The epidural insertion point will be 2 segments upper than the surgical procedure level, 10 ml of Bupivacaine 0.25% will be injected in the epidural space to adjust the sensory level
General anesthesia
Propofol 2-3 mg/kg'Diprivan 1%', Fentanyl 'Fentanyl' 2 μg/kg, and Cisatracurium 'Cisatracure' 0.2 mg/kg will be administered to facilitate endotracheal intubation, and ventilation will be controlled to maintain the end-tidal carbon dioxide (CO2) between 32-38 mmHg, to maintain anesthesia, 2-3% Sevoflurane 'Sevoflurane', and 0.05 mg/kg of the muscle relaxant Cisatracurium will be added at 40-minute intervals according to the conditions of the operation. No other medication will be administered
Local infiltration with Lidocaine HCL 1%'Debocaine'
Lidocaine 1% which is a local analgesic as local infiltration
Faculty of Medicine Ain shams University, Cairo
Ain Shams University
OTHER