Lumbar Epidural Analgesia Versus Local Anesthesia With Dexmedetomidine Infusion in Endoscopic Lumbar Discectomy

NACompletedINTERVENTIONAL
Enrollment

78

Participants

Timeline

Start Date

May 20, 2023

Primary Completion Date

November 30, 2023

Study Completion Date

November 30, 2023

Conditions
Lumbar Disc Herniation
Interventions
DRUG

Dexmedetomidine Hydrochloride 'Precedex' combined with

Dexmedetomidine Hydrochloride which is an Alfa 2 receptor agonist

PROCEDURE

Lumbar epidural analgesia with Bupivacaine 0.25% 'Sunnypivacaine'

The epidural insertion point will be 2 segments upper than the surgical procedure level, 10 ml of Bupivacaine 0.25% will be injected in the epidural space to adjust the sensory level

PROCEDURE

General anesthesia

Propofol 2-3 mg/kg'Diprivan 1%', Fentanyl 'Fentanyl' 2 μg/kg, and Cisatracurium 'Cisatracure' 0.2 mg/kg will be administered to facilitate endotracheal intubation, and ventilation will be controlled to maintain the end-tidal carbon dioxide (CO2) between 32-38 mmHg, to maintain anesthesia, 2-3% Sevoflurane 'Sevoflurane', and 0.05 mg/kg of the muscle relaxant Cisatracurium will be added at 40-minute intervals according to the conditions of the operation. No other medication will be administered

DRUG

Local infiltration with Lidocaine HCL 1%'Debocaine'

Lidocaine 1% which is a local analgesic as local infiltration

Trial Locations (1)

Unknown

Faculty of Medicine Ain shams University, Cairo

All Listed Sponsors
lead

Ain Shams University

OTHER

NCT05850455 - Lumbar Epidural Analgesia Versus Local Anesthesia With Dexmedetomidine Infusion in Endoscopic Lumbar Discectomy | Biotech Hunter | Biotech Hunter