The Viability Control of Human Endothelial Cells Before Keratoplasty (V-CHECK) Study

RecruitingOBSERVATIONAL
Enrollment

135

Participants

Timeline

Start Date

December 1, 2023

Primary Completion Date

March 30, 2026

Study Completion Date

September 30, 2026

Conditions
Corneal Transplant FailureCorneal Endothelial Cell Loss
Interventions
DIAGNOSTIC_TEST

V-Check

Preoperative analysis of endothelial tissue staining with vital dye (Trypan Blue 0.05%) and image analysis to identify the percentage of Trypan Blue Positive Areas, corresponding to dead endothelial cells and/or denuded areas of endothelium, in tissues destined to keratoplasty

Trial Locations (12)

2650

NOT_YET_RECRUITING

Antwerp University Hospital, Edegem

6229

NOT_YET_RECRUITING

Maastricht University Medical Center, Maastricht

25123

RECRUITING

Azienda Socio Sanitaria Territoriale degli Spedali Civili di Brescia, Brescia

29010

NOT_YET_RECRUITING

Hospital Regional Universitario de Málaga, Málaga

30174

NOT_YET_RECRUITING

Fondazione Banca degli Occhi del Veneto, Venice

36100

NOT_YET_RECRUITING

San Bortolo Hospital, Vicenza

40138

NOT_YET_RECRUITING

IRCCS Azienda Ospedaliero-Universitaria di Bologna, Bologna

48149

NOT_YET_RECRUITING

Münster University Hospital, Münster

50937

NOT_YET_RECRUITING

Department of Ophthalmology, University of Cologne, Cologne

88100

NOT_YET_RECRUITING

Department of Medical and Surgical Sciences, University Magna Græcia, Catanzaro

00133

NOT_YET_RECRUITING

Department of Experimental Medicine, Tor Vergata School of Medicine and Surgery, Roma

L7 8YE

NOT_YET_RECRUITING

Royal Liverpool University Hospital, Liverpool

All Listed Sponsors
lead

Azienda Socio Sanitaria Territoriale degli Spedali Civili di Brescia

OTHER