110
Participants
Start Date
September 3, 2024
Primary Completion Date
March 17, 2025
Study Completion Date
March 20, 2025
Postoperative pain management with acetaminophen
During the 24 hours postoperatively, participants will receive 1 g acetaminophen intravenously (i.v.) three times a day. On the second and third postoperative days, participants will receive 1g acetaminophen per os three times a day.
Bilateral TAP Block with levobupivacaine
Ultrasound-guided bilateral TAP block will be performed, and 20 ml of 0,25 % levobupivacaine will be administered to the participant on each side.
Bilateral TAP Block with levobupivacaine and dexmedetomidine
Ultrasound-guided bilateral TAP block will be performed, and 20 ml of 0,25 % levobupivacaine with the addition of 0,5 μg/kg dexmedetomidine will be administered to the participant on each side.
Postoperative pain management with tramadol
During the 24 hours postoperatively, participants will receive 500 mg tramadol + 500 ml 0,9% NaCl i.v. continuously 30ml/h.
Postoperative pain management with ketoprofen
During the 24 hours postoperatively, participants will receive 100 mg ketoprofen + 100 ml of 0,9% NaCl i.v. twice a day. The first dose will be administered in the theatre at the end of the surgical procedure.
Postoperative pain management with ibuprofen
On the second and third postoperative days, participants will receive 600 mg ibuprofen per os three times a day.
University Hospital Center Sestre milosrdnice, Zagreb
University Hospital Sestre Milosrdnice
OTHER