Comparison of Segmentectomy Versus Lobectomy for Lung Adenocarcinoma ≤ 2cm

RecruitingOBSERVATIONAL
Enrollment

446

Participants

Timeline

Start Date

August 20, 2019

Primary Completion Date

April 30, 2028

Study Completion Date

April 30, 2028

Conditions
Lung Adenocarcinoma
Interventions
PROCEDURE

Lobectomy with systemic lymph node dissection

Lobectomy with hilar and mediastinal lymph node dissection is performed. Segmentectomy with hilar and mediastinal lymph node dissection is performed. Systemic or selective lymph node dissection is mandatory, and nodal sampling is not allowed. At least three stations of mediastinal lymph node from 2R, 4R, 7, 8, 9 for the right side and 5, 6, 7, 8, 9 for the left side, respectively. The distance from the dissection margin to the tumor edge must be evaluated intra-operatively. If the distance is either less than the maximum tumor diameter or 20 mm, the absence of cancer cells in the resection margin must be histologically or cytologically confirmed before finishing surgery.

PROCEDURE

Segmentectomy with systemic lymph node dissection

Segmentectomy with hilar and mediastinal lymph node dissection is performed. If the tumor located at inter-segment plane and without sufficient resection margin distance, a combined segmentectomy will be performed. Systemic or selective lymph node dissection is mandatory, and nodal sampling is not allowed. At least three stations of mediastinal lymph node from 2R, 4R, 7, 8, 9 for the right side and 5, 6, 7, 8, 9 for the left side, respectively. The distance from the dissection margin to the tumor edge must be evaluated intra-operatively. If the distance is either less than the maximum tumor diameter or 20 mm, the absence of cancer cells in the resection margin must be histologically or cytologically confirmed before finishing surgery.

Trial Locations (1)

200433

RECRUITING

Shanghai Pulmonary Hospital, Yangpu

All Listed Sponsors
lead

Shanghai Pulmonary Hospital, Shanghai, China

OTHER