NCT05835245View on ClinicalTrials.gov

Cryoablation Combined With Sintilimab Plus Lenvatinib in 1L Treatment of Advanced ICC (CASTLE-ICC-Chemo-free)

PHASE2RecruitingINTERVENTIONAL
Enrollment

30

Participants

Timeline

Start Date

April 28, 2023

Primary Completion Date

December 30, 2025

Study Completion Date

December 30, 2025

Conditions
Advanced Intrahepatic Cholangiocarcinoma
Interventions
PROCEDURE

Cryoablation

Cryoablation is performed under US or CT guidance per Investigator decision.

DRUG

Sintilimab

a PD-1 immune check inhibitor

DRUG

Lenvatinib

Lenvatinib capsules

Trial Locations (1)

200032

RECRUITING

Fudan University Shanghai Cancer Center, Shanghai

All Listed Sponsors
lead

Fudan University

OTHER