The Efficacy of Probiotics for the Treatment of Alcohol Use Disorder Among Adult Males

NANot yet recruitingINTERVENTIONAL
Enrollment

120

Participants

Timeline

Start Date

May 1, 2023

Primary Completion Date

April 30, 2026

Study Completion Date

April 30, 2026

Conditions
Alcohol Use Disorder
Interventions
DIETARY_SUPPLEMENT

Lactobacillus sp. probiotic

The probiotic product contains good bacteria Lactobacillus sp. and primarily maltodextrin as carrier. Sachets of products containing the probiotic appear as light-yellow powder. The probiotic products are kept at storage temperature range below 30oC according to the condition recommended by the manufacturer.

BEHAVIORAL

Acceptance and commitment therapy

The ACT session is initiated by building good therapeutic rapport with the subject and gather important information such as experiential avoidance, external barriers, fusion past, unworkable actions, and strength of the subject, followed by formulation of the case. The session may began with coaching subjects on acknowledging and accepting their unpleasant thoughts and feelings. The therapy will also focus on defusion to reduce behavioral avoidance of unpleasant thoughts and feelings by acknowledging them but focus on the values identified. Mindfulness is also practice to allow focus onto the present and surrounding to create awareness among the subjects that they are many things in the surrounding which is more enjoyable that we can enjoy rather than making effort to distract or change or avoid the unpleasant thoughts and feelings.

DIETARY_SUPPLEMENT

Placebo

The placebo are in powder form prepare in sachet which is light-yellow in color and should be stored in temperature at below 30oC, which is similar to the appearance of the probiotic. Nevertheless, it contains only maltodextrin in same amount as in the placebo.

All Listed Sponsors
collaborator

Xinxiang medical university

OTHER

lead

Universiti Sains Malaysia

OTHER

NCT05830708 - The Efficacy of Probiotics for the Treatment of Alcohol Use Disorder Among Adult Males | Biotech Hunter | Biotech Hunter