Study of Product of Conception Derived From Ultrasound-guided Manual Vacuum Aspiration

RecruitingOBSERVATIONAL
Enrollment

100

Participants

Timeline

Start Date

May 30, 2023

Primary Completion Date

May 31, 2028

Study Completion Date

October 31, 2028

Conditions
Genetic AnticipationImmunological Abnormalities
Interventions
PROCEDURE

Ultrasound-guided manual vaccum

"For managing with miscarriage or termination of pregnancy (TOP) in first trimester loss, ultrasound-guided manual vacuum aspiration (USG-MVA) is one of the treatment options.~The USG-MVA device works by aspirating the uterine content via the cannula into the syringe. Furthermore, product of conception derived from USG-MVA can be sent for karyotyping analysis.~POCs obtained from MVA procedure were rinsed in normal saline thoroughly in the kidney basin to minimize maternal blood. Chorionic villi were considered as a proxy of fetal genetics, appeared to be yellowish in color and tree-projection-like in appearance, floating on the surface of the waterline. Decidua are originated from the mother, appeared substantive in structure and sank in the basin. The two different types of tissues are separated from each other for different testing."

Trial Locations (1)

Unknown

RECRUITING

Prince of Wales Hospital, Hong Kong

All Listed Sponsors
lead

Chinese University of Hong Kong

OTHER