56
Participants
Start Date
May 22, 2023
Primary Completion Date
December 31, 2025
Study Completion Date
December 31, 2025
Vancomycin Continuous Infusion
A precision drug dosing platform will be used to determine the empiric dosing regimen and the dosing parameter targeted will be an area-under-the-curve (AUC) of 500 mg⸱hr/L (range 400-600 mg⸱hr/L). The total daily dose is infused over a period of 24 hours.
Vancomycin Intermittent Infusion
A precision drug dosing platform will be used to determine the empiric dosing regimen and the dosing parameter targeted will be an area-under-the-curve (AUC) of 500 mg⸱hr/L (range 400-600 mg⸱hr/L). The dose is infused at rates of 1 gram per hour in every 8, -12, or -24 hour intervals.
RECRUITING
University of Kentucky, Lexington
National Institute of Allergy and Infectious Diseases (NIAID)
NIH
Aaron Cook
OTHER