240
Participants
Start Date
July 3, 2020
Primary Completion Date
May 21, 2021
Study Completion Date
May 21, 2021
metformin+sibutramine
1 tablet (850 mg + 10 mg) once per day in the morning, without chewing and followed with a glass of water, during meals, for 180 days. At Visit 3 (Day 30 ± 1), in the absence of a 2 kg weight loss compared to Visit1 (Day 1), the zero dose was increased to 1 tablet (850 mg + 15 mg)
sibutramine+ microcrystalline cellulose
1 capsule (10 mg + 158.5 mg) once per day in the morning, without chewing and followed with a glass of water, during meals for, 180 days.At Visit 3 (Day 30 ± 1), in the absence of a 2 kg weight loss compared to Visit 1 (Day 1), the zero dose was increased to 1 capsule (15 mg + 153,5 mg)
Ivanovo Clinical Hospital named after Kuvaev, Ivanovo
Kirov State Medical University, Kirov
Pirogov Russian National Research Medical University, Moscow
"Rostov State Medical University of the Ministry of Health of the Russian Federation", Rostov-on-Don
"Clinical hospital RZD-Medicine of the city of St. Petersburg", Saint Petersburg
Avrora Limited Liability Company Principal, Saint Petersburg
"Limited Liability Company Medica", Saint Petersburg
OrKli Hospital Limited Liability Company, Saint Petersburg
Promomed, LLC
OTHER