Bladder and Bone Effects of Pelvic Radiation Therapy in Childhood Cancer Survivors

RecruitingOBSERVATIONAL
Enrollment

60

Participants

Timeline

Start Date

July 11, 2023

Primary Completion Date

December 31, 2025

Study Completion Date

December 31, 2026

Conditions
CancerChildhood Cancer
Interventions
DIAGNOSTIC_TEST

Uroflow testing

Uroflowmetry is a test that measures the volume of urine released from the body, the speed with which it is released, and how long the release takes.

DIAGNOSTIC_TEST

Bladder Scan

Bladder scan measures ultrasonic reflections within the patient's body to differentiate the urinary bladder from the surrounding tissue. In this case, it is used to detect the volume of urine in the bladder.

OTHER

Dysfunctional Voiding Scoring System Survey

The Dysfunctional Voiding Symptom Score to provide accurate and objective numerical, grading of voiding behaviors of children.

DIAGNOSTIC_TEST

DEXA Scan of pelvis and sacral spine

DEXA (dual x-ray absorptiometry) scans measure bone density (thickness and strength of bones) by passing a high and low energy x-ray beam (a form of ionizing radiation) through the body, usually in the hip and the spine.

DIAGNOSTIC_TEST

Urine tests for specific biomarkers

Urine tests for specific biomarkers (ATP, NGF, BNDF and urine proteomic screening).

Trial Locations (1)

80217

RECRUITING

Colorado Research Center, Aurora

All Listed Sponsors
lead

University of Colorado, Denver

OTHER