"Physiological vs Right Ventricular Pacing Outcome Trial Evaluated for bradyCardia Treatment (PROTECT-HF)"

NARecruitingINTERVENTIONAL
Enrollment

2,600

Participants

Timeline

Start Date

June 5, 2023

Primary Completion Date

December 4, 2029

Study Completion Date

December 4, 2029

Conditions
BradycardiaPacingRight Ventricular PacingHis Bundle PacingLeft Bundle Branch Area Pacing
Interventions
DEVICE

Pacemaker - Physiological pacing

The approach for physiological pacing will be either His bundle pacing or left bundle pacing at the operator's discretion. If both of these are not achieved biventricular pacing will be performed.

DEVICE

Pacemaker - Right Ventricular pacing

Right ventricular pacing (apical or septal lead locations as per the implanting physicians' normal practice).

Trial Locations (45)

Unknown

RECRUITING

Beacon Hospital, Dublin

RECRUITING

Univerisity Medical Centre Ljubljana, Ljubljana

RECRUITING

Aberdeen Royal Infirmary, Aberdeen

RECRUITING

Queen's Hospital, Barking

RECRUITING

Good Hope Hospital, Birmingham

RECRUITING

Queen Elizabeth Hospital, Birmingham

RECRUITING

University Hospital Dorset, Bournemouth

RECRUITING

Royal SUSSEX County Hospital, Brighton

RECRUITING

Bristol Heart Institute, Bristol

RECRUITING

Royal Papworth Hospital, Cambridge

RECRUITING

St Richard's Hospital, Chichester

RECRUITING

University Hospital Coventry, Coventry

RECRUITING

Croydon, Croydon

RECRUITING

Royal Infirmary of Edinburgh, Edinburgh

RECRUITING

Victoria Hospital, Fife Keith

RECRUITING

Medway Maritime Hospital, Gillingham

RECRUITING

Wycombe Hospital, High Wycombe

RECRUITING

Forth Valley Royal Hospital, Larbert

RECRUITING

Leeds Teaching Hospital, Leeds

RECRUITING

Glenfield Hospital, Leicester

RECRUITING

Liverpool Heart and Chest Hospital, Liverpool

RECRUITING

Hammersmith Hospital, London

RECRUITING

Kettering Hospital, London

RECRUITING

King's College Hospital, London

RECRUITING

Royal Free London/ Barnet Hospital, London

RECRUITING

St Bartholomew's Hospital, London

RECRUITING

Watford General Hospital, London

RECRUITING

James Cook Hospital, Middlesbrough

RECRUITING

King's Mill Hospital, Nottingham

RECRUITING

Nottingham City Hospital, Nottingham

RECRUITING

John Radcliffe Hospital, Oxford

RECRUITING

Derriford Hospital, Plymouth

RECRUITING

Queen Alexandra Hospital, Portsmouth

RECRUITING

Royal Berkshire, Reading

RECRUITING

East Surrey, Redhill

RECRUITING

Rotherham General Hospital, Rotherham

RECRUITING

Northern General, Sheffield

RECRUITING

Wexham Park Hospital, Slough

RECRUITING

Southampton, Southampton

RECRUITING

Morriston Hospital, Swansea

RECRUITING

Great Western, Swindon

RECRUITING

Musgrove Park Hospital, Taunton

RECRUITING

Torbay Hospital, Torquay

RECRUITING

UHS Worthing, Worthing

RECRUITING

York Hospital, York

All Listed Sponsors
collaborator

British Heart Foundation

OTHER

lead

Imperial College London

OTHER