ctDNA-guided Adjuvant Chemotherapy in Liver Metastasis of Colorectal Cancer

PHASE3RecruitingINTERVENTIONAL
Enrollment

490

Participants

Timeline

Start Date

February 20, 2023

Primary Completion Date

February 20, 2031

Study Completion Date

February 20, 2033

Conditions
Colorectal CancerLiver MetastasesCirculating Tumor CellChemotherapy Effect
Interventions
PROCEDURE

Colorectal cancer resection combined with liver metastasis resection.

The preferred surgical approach is resection of the corresponding colon segment with regional lymph node dissection. If conditions permit, synchronous resection of the primary lesion and liver metastases of colorectal cancer can be performed to achieve curative resection.

DRUG

FOLFOX chemotherapy regimen

Chemotherapy regimens recommended include oxaliplatin-based CapeOx or FOLFOX regimens, or single-agent 5-FU/LV, capecitabine, or combination with targeted therapy.

Trial Locations (1)

Unknown

RECRUITING

The Sixth Affiliate Hospital of Sun Yat-Sen University, Guangzhou

All Listed Sponsors
lead

Sixth Affiliated Hospital, Sun Yat-sen University

OTHER