The Safety of Etomidate - Propofol Mixture vs Propofol in Total Intravenous Anesthesia During Abdominal Surgery

NACompletedINTERVENTIONAL
Enrollment

468

Participants

Timeline

Start Date

June 16, 2023

Primary Completion Date

June 17, 2024

Study Completion Date

October 30, 2024

Conditions
EtomidateHypotension
Interventions
DRUG

Etomidate - propofol mixture

Patients will receive etomidate - propofol mixture during induction and maintenance. Sufentanil 0.2-0.7 μg/kg,Cisatracurium 0.15 mg/kg,EP mixture(E:P=1:2) 0.1-0.25 ml/kg for induction, EP mixture 0.4\~ 1.2 ml/kg/h and remifentanil 0.05μg/kg/min \~0.3 μg/kg/min for maintenance.

DRUG

Propofol

Patients will receive propofol during induction and maintenance.Sufentanil 0.2-0.7 μg/kg,Cisatracurium 0.15 mg/kg,propofol 0.1-0.25 ml/kg for induction, propofol 0.4\~ 1.2 ml/kg/h and remifentanil 0.05μg/kg/min \~0.3 μg/kg/min for maintenance.

Trial Locations (1)

Unknown

Tongji hospital, Wuhan

All Listed Sponsors
lead

Ailin Luo

OTHER