Intranasal Cocaine and Temperature Regulation During Exercise

PHASE1/PHASE2CompletedINTERVENTIONAL
Enrollment

27

Participants

Timeline

Start Date

September 1, 2023

Primary Completion Date

June 5, 2024

Study Completion Date

August 1, 2024

Conditions
HyperthermiaCocaine UseExercise
Interventions
DRUG

Cocaine

Cocaine (cocaine hydrochloride 4% nasal solution) will be administered (3 mg/kg) intranasally prior to entering the warm environmental conditions and performing 60 minutes of exercise.

DRUG

Lidocaine

Lidocaine (lidocaine hydrochloride 4% nasal solution) will be administered (3 mg/kg) intranasally prior to entering the warm environmental conditions and performing 60 minutes of exercise.

Trial Locations (1)

75390

University of Texas Southwestern Medical Center, Dallas

All Listed Sponsors
lead

University of Texas Southwestern Medical Center

OTHER

NCT05809453 - Intranasal Cocaine and Temperature Regulation During Exercise | Biotech Hunter | Biotech Hunter