HFNO in Pneumonia Patients Presenting With Acute Hypoxemic Respiratory Failure

NACompletedINTERVENTIONAL
Enrollment

200

Participants

Timeline

Start Date

November 20, 2020

Primary Completion Date

January 20, 2023

Study Completion Date

February 20, 2023

Conditions
Pneumonia
Interventions
DEVICE

High flow nasal cannula (HFNC)

"High-flow nasal cannula device was utilized. Humidifier temperature was set at 37°C via large-bore bi-nasal prongs, and inspired oxygen (FiO2) was adjusted to maintain oxygen saturation by pulse oximetry (SpO2) ≥ 90%.The flow was initially set at 10 L/min and titrated upward in 5 L/min steps until patients experienced discomfort.~Patient will be evaluated every 8 hours and discontinued the device for eating, drinking and coughing up secretion and returned back to the device for 72 hours."

DEVICE

Noninvasive ventilation (NIV)

Patients initiated NIV; Inspiratory positive airway pressure (IPAP) was initiated at 10-12 cmH2O, and expiratory positive airway pressure (EPAP) started at 4-5 cmH2O. FIO2 was adjusted to maintain SpO2 ≥ 90%. The same protocol as done in HFNC, patient will be evaluated every 8 hours and discontinued the device and returned back to the device for re- evaluation within 72 hours

Trial Locations (1)

Unknown

Doaa Magdy Eid, Asyut

All Listed Sponsors
lead

Assiut University

OTHER

NCT05809089 - HFNO in Pneumonia Patients Presenting With Acute Hypoxemic Respiratory Failure | Biotech Hunter | Biotech Hunter