Cerebral Perfusion Variation During Blood Pressure Changes in ICU

RecruitingOBSERVATIONAL
Enrollment

92

Participants

Timeline

Start Date

July 20, 2023

Primary Completion Date

July 31, 2025

Study Completion Date

November 30, 2025

Conditions
Intensive Care Unit Syndrome
Interventions
DIAGNOSTIC_TEST

Non-invasive Measurement of cerebral blood velocity in the middle cerebral artery by transcranial pulsed Doppler (TCD) (Mean velocity, Vm, cm/s)

"Measurement of cerebral blood velocity in the middle cerebral artery by transcranial pulsed Doppler (TCD) (Mean velocity, Vm, cm/s) (recorded on Data Warehouse Connect).~For all patients Vm in (cm/s) will be collected during the adjustment of the mean arterial pressure level between 90% and 70% of the baseline value, without ever going below 60 mmHg for the patients at low risk and 80 mmHg for the patients at high cardiovascular risk. For neuro-injured patients with intracranial pressure monitoring (ICP), the lower limit of cerebral perfusion pressure (CPP = MAP - ICP) will be set at 50 mmHg"

Trial Locations (1)

75010

RECRUITING

Hôpital Lariboisière, Paris

All Listed Sponsors
collaborator

INSERM UMR-942, Paris, France

OTHER

collaborator

LMS Polytechnique and M3DISIM, Inria

UNKNOWN

lead

Assistance Publique - Hôpitaux de Paris

OTHER