Nicotine Influence on the Retina Following the Use of Electronic Cigarette

NACompletedINTERVENTIONAL
Enrollment

44

Participants

Timeline

Start Date

August 25, 2022

Primary Completion Date

November 23, 2023

Study Completion Date

November 23, 2023

Conditions
Electronic Cigarette UseRetina; Change
Interventions
DEVICE

RETI-port/scan 21

Pattern visual event-related potential and pattern electroretinogram on right eye (non-dilated pupil) at baseline, post e-cigarette vaping without nicotine and post e-cigarette vaping with nicotine.

DEVICE

Zilia Ocular

Eye fundus tissue oximetry measure on left eye (dilated pupil) at baseline, post e-cigarette vaping without nicotine and post e-cigarette vaping with nicotine.

DEVICE

OCT-A

Optical coherence tomography angiography measure on left eye (dilated pupil) at baseline, post e-cigarette vaping without nicotine and post e-cigarette vaping with nicotine.

COMBINATION_PRODUCT

Electronic cigarette without nicotine

Vaping using an e-cigarette paired with an e-cigarette liquid vial without nicotine. Inhaling through the mouth and exhaling through the nose ten times. Inhalations must last 5 seconds and the participant has 5 minutes to do the 10 inhalations.

COMBINATION_PRODUCT

Electronic cigarette with nicotine

Vaping using an e-cigarette paired with an e-cigarette liquid vial with nicotine. Inhaling through the mouth and exhaling through the nose ten times. Inhalations must last 5 seconds and the participant has 5 minutes to do the 10 inhalations.

Trial Locations (1)

H3T 1P1

École d'optométrie de l'Université de Montréal, Montreal

All Listed Sponsors
lead

Christian Casanova

INDUSTRY