(68^Ga)-GaPSMA-11 PET/MR-imaging of Malignant Intra-axial Brain Tumors

NACompletedINTERVENTIONAL
Enrollment

12

Participants

Timeline

Start Date

September 1, 2020

Primary Completion Date

March 1, 2023

Study Completion Date

March 31, 2023

Conditions
Malignant Brain Tumors
Interventions
PROCEDURE

intra-arterial injection

"All patients will receive an intravenous injection of \[68Ga\]Ga-PSMA-11 (1.5 MBq/kg), followed by a synchronous PET/MRI scan (median duration approximately 50 min) at 45-60 min post-injection.~In case of a positive \[68Ga\]Ga-PSMA-PET signal at the tumor site, patients will return (in 2 weeks) for an intra-arterial injection (i.e., a neuro-interventional procedure) of 68Ga-PSMA-11 (1.5 MBq/kg), followed by a repeat synchronous PET/MRI scan (median duration 50 min) at 45-60 min post-injection."

DEVICE

synchronous PET/MRI scan

Scan done at (median duration approximately 50 min) at 45-60 min post-injection.

OTHER

Radiopharmacon Contrast agent

Type: \[68Ga\]Ga-PSMA-11 dosage: 1.5 MBq/kg

Trial Locations (1)

2651GG

Laurens Groenendijk, Berkel en Rodenrijs

Sponsors
All Listed Sponsors
lead

Erasmus Medical Center

OTHER