NCT05794880View on ClinicalTrials.gov

MCW Alpha/Beta T-Cell and B-Cell Depletion With Targeted ATG Dosing

NARecruitingINTERVENTIONAL
Enrollment

40

Participants

Timeline

Start Date

May 1, 2023

Primary Completion Date

May 31, 2027

Study Completion Date

May 31, 2032

Conditions
LeukemiaAcute Myeloid Leukemia in RemissionMyelodysplasiaAcute Lymphoblastic Leukemia in RemissionChronic Myelogenous Leukemia - Chronic PhaseChronic Myelogenous Leukemia, Accelerated PhaseChronic Myelogenous Leukemia With Crisis of Blast CellsBiphenotypic Acute LeukemiaLymphoblastic LymphomaBurkitt LymphomaBurkitt LeukemiaLymphoma After RelapseOther Malignant Hematologic Diseases in Remission
Interventions
DEVICE

Magnetic-Activated Cell Sorter (CliniMACS, Miltenyi)

Participants in this study will receive a blood stem cell transplant, which will use an investigational device called the CliniMACs device to remove alpha/beta T cells and B cells from the blood cells collected from the donor. This is called T cell depletion and B cell depletion.

Trial Locations (1)

53226

RECRUITING

Children's Wisconsin, Milwaukee

All Listed Sponsors
lead

Medical College of Wisconsin

OTHER