Impact of Hypofractionated Radiotherapy Strategy After Surgery of Skin Carcinomas in Older Patients

NARecruitingINTERVENTIONAL
Enrollment

303

Participants

Timeline

Start Date

October 17, 2023

Primary Completion Date

March 1, 2028

Study Completion Date

March 1, 2028

Conditions
Skin Cancer, Non-Melanoma
Interventions
OTHER

Surgery with additional moderate hypofractionation RT (15 fractions)

"After randomization, patients will then be followed-up at 3 months post randomization and at each surveillance visit (M6, M12, M24 and M36).~Adjuvant Radiotherapy:~-Arm B: Surgery followed by moderate hypofractionation RT (15 fractions): 45Gy in 15 fractions, 3 fractions per week over 5 weeks to the operative bed."

OTHER

Surgery alone, without radiation post surgery

Arm A: Surgery alone followed by surveillance

RADIATION

Surgery with extreme hypo fractionation treatment (HF)

"After randomization, patients will then be followed-up at 3 months post randomization and at each surveillance visit (M6, M12, M24 and M36).~Adjuvant Radiotherapy:~-Arm C= Surgery followed by extreme hypofractionation RT (5 fractions, 2 fractions/week): 30Gy in 5 fractions of 6Gy over 5 weeks to the operative bed."

Trial Locations (1)

94000

RECRUITING

Henri Mondor, Créteil

All Listed Sponsors
lead

Assistance Publique - Hôpitaux de Paris

OTHER