Effects of Permissive Hypercapnia on Concentration of Postoperative Plasma Neurofilament Light

NACompletedINTERVENTIONAL
Enrollment

84

Participants

Timeline

Start Date

April 1, 2023

Primary Completion Date

January 28, 2024

Study Completion Date

January 28, 2024

Conditions
Hypercapnia
Interventions
BEHAVIORAL

permissive hypercapnia

Tidal volume (6-8ml/kg) and respiratory rate is adjusted to achieve the objective values of PaCO2:45~55mmHg

BEHAVIORAL

normocapnia

Tidal volume (8-10ml/kg) and respiratory rate is adjusted to achieve the objective values of PaCO2:35~45mmHg

Trial Locations (1)

314000

Affiliated Hospital of Jiaxing University, Jiaxing

All Listed Sponsors
lead

Affiliated Hospital of Jiaxing University

OTHER