Clinical Study to Evaluate the Possible Efficacy of Dapagliflozin and Atorvastatin in Patients With Major Depressive Disorders

PHASE2CompletedINTERVENTIONAL
Enrollment

75

Participants

Timeline

Start Date

June 6, 2023

Primary Completion Date

November 20, 2024

Study Completion Date

December 20, 2024

Conditions
Depressive Disorder
Interventions
DRUG

Fluoxetine 20 mg

Fluoxetine is a type of antidepressant known as a selective serotonin reuptake inhibitor (SSRI). It's often used to treat depression, and sometimes obsessive-compulsive disorder and bulimia. It works by increasing the levels of serotonin in the brain

DRUG

Dapagliflozin 10mg Tab

Dapagliflozin (DAPA), a sodium-glucose co-transporter 2 inhibitor (SGLT2-I), has proven to be an effective hyperglycemic suppressor due to its role in inhibiting the reabsorption of 30-50% of the glucose filtered by the kidney, besides its role in the improvement of insulin resistance

DRUG

Atorvastatin 80mg

Atorvastatin is a synthetic and lipophilic statin, a class of drugs used in the treatment of hypercholesterolemia

Trial Locations (1)

32511

Faculty of Medicine, Menoufia University, Tanta

All Listed Sponsors
collaborator

Manal Ali Mahrous Hamouda Faculty of Pharmacy, Menufia University

UNKNOWN

lead

Tanta University

OTHER

NCT05792540 - Clinical Study to Evaluate the Possible Efficacy of Dapagliflozin and Atorvastatin in Patients With Major Depressive Disorders | Biotech Hunter | Biotech Hunter