Ischemic Post-conditioning in Acute Ischemic Stroke Thrombectomy (PROTECT-2)

PHASE2RecruitingINTERVENTIONAL
Enrollment

160

Participants

Timeline

Start Date

November 1, 2023

Primary Completion Date

November 1, 2025

Study Completion Date

February 1, 2026

Conditions
Acute Ischemic Stroke
Interventions
PROCEDURE

Mechanical thrombectomy combined with ischemic post-conditioning

Ischemic post-conditioning will be applied after successful recanalization of the culprit artery achieve by thrombectomy. Ischemic post-conditioning consists of briefly repeated 4 cycles × 2 minutes of occlusion and reperfusion (equal duration) of the initially occluded artery using a balloon.

PROCEDURE

Mechanical thrombectomy alone

Successful recanalization was achieved by mechanical thrombectomy without subsequent ischemic post-conditioning.

Trial Locations (1)

300350

RECRUITING

Tianjin Huanhu Hospital, Tianjin

All Listed Sponsors
lead

Capital Medical University

OTHER