Transcutaneous Vagus Nerve Stimulation in Heart Failure

NACompletedINTERVENTIONAL
Enrollment

29

Participants

Timeline

Start Date

June 15, 2020

Primary Completion Date

September 30, 2024

Study Completion Date

December 31, 2024

Conditions
Heart Failure With Preserved Ejection FractionHeart Failure With Midrange Ejection Fraction
Interventions
DEVICE

Active tVNS

It is a non-invasive transcutaneous electrical stimulation of the auricular branch of the vagus nerve which innervates the skin of the human ear. These nerve fibers project directly to the solitary tract nucleus (NTS) in the brain stem (6).

DEVICE

Sham tVNS

Sham stimulation is obtained by placing the stimulation electrode at the level of the earlobe. The stimulation is therefore administered and perceived in an area not innervated by vagal fibers.

Trial Locations (1)

27100

Istituti Clinici Scientifici Maugeri IRCCS, Pavia

All Listed Sponsors
lead

Istituti Clinici Scientifici Maugeri SpA

OTHER

NCT05789147 - Transcutaneous Vagus Nerve Stimulation in Heart Failure | Biotech Hunter | Biotech Hunter