148
Participants
Start Date
October 8, 2022
Primary Completion Date
December 31, 2025
Study Completion Date
December 31, 2025
Mevalproic acid
Methovalerate pathway is a metabolism of cholesterol and isoprenoid synthesized from acetyl coenzyme A Pathway, which plays a key role in human health and disease, is also necessary for human cells to maintain normal functions. There are a series of important metabolic intermediates in the mevalproate pathway, such as farnesyl diphosphate and incense Folyl vanillin diphosphates, which modify proteins through isoprene, play an important role in regulating cell function. In addition, the latest research shows that valproic acid, the key metabolic intermediate of valproic acid pathway, being the synthetic precursor of cholesterol and isoprene, it can activate insulin growth factor (IGF)1-R and mTOR signals and maintain cell function by mediating histone function
RECRUITING
Reproductive Medicine Center, The affiliated Drum Towel Hospital of Nanjing University Medical School, Nanjing
Nanjing University
OTHER